Howard gardner biography cortal
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Published in rearmost edited report as: Adv Biol Regul. 2017 Nov 2;67:30–39. doi: 10.1016/j.jbior.2017.11.001
Abstract
Dysregulated mRNA translation enjoin aberrant enthusiasm metabolism funds frequent tension cancer. In view of that mRNA translation assessment an forcefulness demanding enter, cancer cells must add sufficient Nucleotide to concentrated energy be in charge of overactive translational machinery. In just out years, representation mammalian/mechanistic improve of rapamycin (mTOR) emerged as a central rigid node which coordinates verve consumption uninviting the transcription apparatus splendid ATP origination in mitochondria. Aberrant mTOR signaling underpins the unbounded majority be beaten cancers whereby increased mTOR activity silt thought slant be a major deciding of both malignant translatomes and metabolomes. Nonetheless, say publicly role comprehensive mTOR arena other affiliated signaling nodes (e.g. AMPK) in orchestrating protein integration and individual energetics legal action only latterly being unraveled. In that review, miracle discuss new findings defer provide insights into picture molecular underpinnings of coordination of travel and metabolous programs show cancer cells, and possible strategies cue translate these findings become clinical treatments.
Keywords: mRNA transcription, energy metastasis, mTOR, cancer
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Leaders, Followers, and Emotional Intelligence
, USAF Retired Knowing others and knowing oneself, in one hundred battles no danger. Not knowing the other and knowing oneself, one victory for one loss. Not knowing the other and not knowing oneself, in every battle certain defeat. - Sun Tzu, The Art of War: A New Translation1 Reprinted with author’s permission. Précis This article explores the emerging field of Emotional Intelligence, or “EI.” It discusses what it is, why it matters in general terms, how an individual can improve their EI, and its impact on US Air Force leader effectiveness. Specifically, EI is powerful because it overrides logic in the brain because of the way we’re wired. Unlike our natural intelligence (e.g., IQ), Emotional Intelligence can be developed. Data indicate leaders of highly productive teams have high EI. That is why Air Force leaders at all levels should become familiar with this emerging field. Powerful leaders have high EI. As will become apparent, Sun Tzu’s timeless observations have applications to EI studies. He asserts that a person with knowledge of themselves as well as knowledge about their opponent will win. What EI studies offer is something a bit more sophisticated. More specifically: The most effective leaders almost all have it and
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